A2M (Alpha-2-Macroglobulin) is a protein that naturally occurs in plasma that blocks proteins that are responsible for creating arthritis in the body. By harvesting a patient’s A2M and re-injecting the super concentrated A2M mixture into the diseased joint, the progression of arthritis (specifically osteoarthritis) can be stopped as well as preventing further loss of cartilage, promoting tissue growth and relief from inflammation/pain.
How it Works
The body naturally produces protein classes that degrade cartilage when the joint is injured. A2M is a powerful inhibitor of three specific protein classes that cause cartilage to breakdown: Cytokines, Matrix Metalloproteinases and A Disintegrin and Metalloproteinase with Thrombospondin. By blocking these proteins, A2M injections can stop the progression of Osteoarthritis (once those proteins are trapped the body can eliminate them quickly) as well as support cartilage restoration.
How it's Done
Blood is collected from the patient and then processed using an Alpha 2 Macroglobulin concentrator with a centrifuge and filtration system. The super concentrated amount of A2M is now ready to be injected into the patient’s affected joint using ultrasound guidance.
After the procedure, the patient will experience minimal discomfort for 3-5 days. Patients may begin to experience pain relief in 4-6 weeks. Patients are monitored by the doctor until the patient can completely return to pre-procedural activities. The regenerative process continues to work over a period of 6 months to a year with most patients continuing to improve in function/movement and decreasing in inflammation/pain.*
New Jersey Regenerative Institute | 197 Ridgedale Avenue, Suite 210, Cedar Knolls, New Jersey 07927 | 973-998-8309
Results may vary based on individual’s overall health, lifestyle, severity of the orthopedic condition being treated and responses are not guaranteed. The information on this site is solely for purposes of general patient education, and may not be relied upon as a substitute for professional medical care. Consult your own physician for evaluation and treatment of your specific condition.